Inspiring repurposing research presentations by six researchers from five Chicago-area institutions.
Dr. George Havelka of the University of Illinois at Chicago and Dr. Darwin Eton presented the winning project, “Saving Limbs: Helping Nature Do Its Magic,” which addresses treatment for chromic limb-threatening ischemia (CLI). CLI patients suffer from impeded blood flow to their limbs, resulting in pain, tissue damage and potentially amputation. The research team has found that combining a compression device with an FDA approved drug used in cancer patients improves patient outcomes and reduces amputation rates. The funding they received will support a clinical study of CLI patients to better understand the molecular effects of the repurposed treatment. Results from this study can then be used to support a larger clinical trial.